Load on startup i.e. the last option in the setting window is to be used when you want PicBackMan to load whenever system is booted. If this option is un-checked, PicBackMan will not load on startup.
PicBackMan is a free photo/video uploader that helps you to keep your memories backed up to your favorite online services.
Users in 130+ countries have backed up.
... an excellent job of uploading more then 300GB of photos to 2 different services